BDBM215157 US9296736, 108::US9593129, Example 108

SMILES C[C@]1(CC(O)=O)C[C@@H]([C@H](N(C1=O)c1cnccn1)c1ccc(Cl)cc1)c1cccc(Cl)c1

InChI Key InChIKey=KRQGGBHSBXARDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215157   

LigandChemical structure of BindingDB Monomer ID 215157BDBM215157(US9296736, 108 | US9593129, Example 108)
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215157BDBM215157(US9296736, 108 | US9593129, Example 108)
Affinity DataIC50: 110nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
US Patent