BDBM215308 US9296736, 269::US9593129, Example 269
SMILES C[C@]1(CC(O)=O)C[C@@H]([C@H](N([C@H](CN(C(F)F)S(=O)(=O)C2CC2)C2CC2)C1=O)c1ccc(Cl)cc1)c1cccc(Cl)c1
InChI Key InChIKey=OZMHBZLIMQZSOG-HIJQLYNKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 215308
Affinity DataIC50: 0.100nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
TargetCellular tumor antigen p53 [1-83]/E3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen
US Patent
Amgen
US Patent
Affinity DataIC50: 0.100nMpH: 7.4 T: 25°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair