BDBM215434 US9296736, 422::US9593129, Example 422

SMILES CC[C@@H](CN1CCCS1(=O)=O)N1[C@@H]([C@H](C[C@@H](Cc2cccc(O)n2)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1

InChI Key InChIKey=PNCDGXOHOAFJKW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 215434   

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 215434BDBM215434(US9296736, 422 | US9593129, Example 422)
Affinity DataIC50: 104nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 215434BDBM215434(US9296736, 422 | US9593129, Example 422)
Affinity DataIC50: 104nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent