BDBM21643 CGS-31,447::[3-(naphthalen-1-yl)-1-{[(1S)-2-(4-phenylphenyl)-1-(1H-1,2,3,4-tetrazol-5-yl)ethyl]amino}propyl]phosphonic acid

SMILES OP(O)(=O)C(CCc1cccc2ccccc12)N[C@@H](Cc1ccc(cc1)-c1ccccc1)c1nnn[nH]1

InChI Key InChIKey=HIILOVHYWAEGDS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21643   

TargetNeprilysin(Rabbit)
Cnrs

LigandPNGBDBM21643([3-(naphthalen-1-yl)-1-{[(1S)-2-(4-phenylphenyl)-1...)
Affinity DataKi:  2.20nM ΔG°:  -12.3kcal/molepH: 7.4 T: 2°CAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
LigandPNGBDBM21643([3-(naphthalen-1-yl)-1-{[(1S)-2-(4-phenylphenyl)-1...)
Affinity DataKi:  10.8nMAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed
LigandPNGBDBM21643([3-(naphthalen-1-yl)-1-{[(1S)-2-(4-phenylphenyl)-1...)
Affinity DataKi: >1.00E+4nMAssay Description:NEP was preincubated in black 96-well microplates with or without increasing concentrations of inhibitors. DGPA was added, and the reaction was stopp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2008
Entry Details Article
PubMed