BDBM217082 US9302989, 377
SMILES O=C(Nc1ccc(cc1)-c1n[nH]c(=O)c2CCCCc12)N1Cc2ccccc2C1
InChI Key InChIKey=LUJABRZNRKRZRI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 217082
Affinity DataKi: 19.5nMAssay Description:HTRF assay: This assay used the CisBio HTRF KinEASE kit (kit 62ST2PEZ) and the kinase reaction containing 0.2 uM biotinylated substrate peptide (S2, ...More data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Inhibition of ROCK2 (unknown origin) using S6-peptide as substrate in presence of [33P]-ATP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant human C-terminally-His tagged NAMPT incubated for 2 to 3 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMpH: 7.5Assay Description:Probe 1:The assay was carried out in 18 uL low volume plates (Owens Corning) in reaction buffer (50 mM HEPES (NaOH), pH 7.5, 100 mM NaCl, 10 mM MgCl2...More data for this Ligand-Target Pair