BDBM21773 2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid::Indanylacetic Acid Analog, 17t

SMILES CCOc1cc(C)ccc1OCCCOc1ccc2[C@H](CC(O)=O)CCc2c1

InChI Key InChIKey=OKYICBFIEIXCLZ-SFHVURJKSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 21773   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21773(2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,...)
Affinity DataEC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21773(2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,...)
Affinity DataEC50:  2.20nMT: 2°CAssay Description:Activity was assessed by measuring the human PPAR ligand binding domain with the co-activator protein. Europium labeled anti-GST antibody, streptavid...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21773(2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,...)
Affinity DataEC50:  8.13E+5nMAssay Description:Agonist activity at Homo sapiens (human) PPARgamma expressed in mouse 3T3-L1 cells incubated for 2 days followed by compound wash out measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Bayer Healthcare Pharmaceuticals

LigandPNGBDBM21773(2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,...)
Affinity DataEC50:  4.55E+8nMAssay Description:Agonist activity at GST-tagged Homo sapiens (human) PPARdelta ligand binding domain after 2 hr by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM21773(2-[(1S)-5-[3-(2-ethoxy-4-methylphenoxy)propoxy]-2,...)
Affinity DataEC50:  1.24E+3nMT: 2°CAssay Description:PPAR gamma activity was assessed by using the IRBA in mouse 3T3-L1 cells. This assay measures the ability of test compound to cause an increase in th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed