BDBM218231 US9249087, Table 1 , Compound 8

SMILES ONC(=O)c1ccc(cc1)-n1cnc2cncnc12

InChI Key InChIKey=IDTVZTNWVIKYPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218231   

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM218231(US9249087, Table 1 , Compound 8)
Affinity DataIC50: 3.48nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM218231(US9249087, Table 1 , Compound 8)
Affinity DataIC50: 940nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent