BDBM218233 US9249087, Table 1 , Compound 10

SMILES ONC(=O)c1ccc(cc1)-c1ccncc1

InChI Key InChIKey=VHFXDBDQQSFQEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218233   

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM218233(US9249087, Table 1 , Compound 10)
Affinity DataIC50: 35.8nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM218233(US9249087, Table 1 , Compound 10)
Affinity DataIC50: 6.47E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent