BDBM218242 US9249087, Table 1 , Compound 19

SMILES CC(C)C(C(C)C)c1ccc(cc1)C(=O)NO

InChI Key InChIKey=BQTJJISIRYOWRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 218242   

TargetHistone deacetylase 6(Human)
University of Illinois

US Patent
LigandPNGBDBM218242(US9249087, Table 1 , Compound 19)
Affinity DataIC50: 124nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
University of Illinois

US Patent
LigandPNGBDBM218242(US9249087, Table 1 , Compound 19)
Affinity DataIC50: 1.92E+3nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
University of Illinois

US Patent
LigandPNGBDBM218242(US9249087, Table 1 , Compound 19)
Affinity DataIC50: 2.38E+4nMpH: 8.0Assay Description:HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent