BDBM218247 US9260435, 5

SMILES CCOC(=O)c1cn2c(c(nc2cn1)-c1ccc(cc1)C1(N)CCC1)-c1ccccc1

InChI Key InChIKey=PNIPDZDFPOPOTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 218247   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM218247(US9260435, 5)
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:His-tagged human recombinant kinase full-length Akt1 expressed in insect cells was purchased form Invitrogen (part number PV 3599). As substrate for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent

TargetRAC-beta serine/threonine-protein kinase(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM218247(US9260435, 5)
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased from Invitrogen (part number PV 39...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
US Patent