BDBM21869 2,9-disubstituted 6-oxopurine, 3::9-(4-hydroxybutyl)-2-(phenylsulfanyl)-6,9-dihydro-3H-purin-6-one

SMILES OCCCCn1cnc2c1nc(Sc1ccccc1)[nH]c2=O

InChI Key InChIKey=LBWXYROZKFEXSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21869   

TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21869(9-(4-hydroxybutyl)-2-(phenylsulfanyl)-6,9-dihydro-...)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetThymidine kinase(HHV-2)
Glsynthesis

LigandPNGBDBM21869(9-(4-hydroxybutyl)-2-(phenylsulfanyl)-6,9-dihydro-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed