BDBM21882 2,9-disubstituted 6-oxopurine, 12f::2-(phenylamino)-9-[4-(piperidin-1-yl)butyl]-6,9-dihydro-3H-purin-6-one dihydrochloride

SMILES O=c1[nH]c(Nc2ccccc2)nc2n(CCCCN3CCCCC3)cnc12

InChI Key InChIKey=MKEDFVCNAXDUFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21882   

TargetThymidine kinase(HHV-2)
Glsynthesis

LigandPNGBDBM21882(2,9-disubstituted 6-oxopurine, 12f | 2-(phenylamin...)
Affinity DataIC50:  220nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(HHV-1)
Glsynthesis

LigandPNGBDBM21882(2,9-disubstituted 6-oxopurine, 12f | 2-(phenylamin...)
Affinity DataIC50:  1.60E+3nMpH: 7.5 T: 37°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed