BDBM21918 8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-{[(6-methylpyridin-2-yl)methyl]amino}quinoline-3-carbonitrile::Cyanoquinoline, 31

SMILES Cc1cccc(CNc2cc(Cl)c3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)n1

InChI Key InChIKey=AGOVQCJRUFATTM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21918   

LigandPNGBDBM21918(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-{[(6...)
Affinity DataIC50: 170nMpH: 7.2 T: 2°CAssay Description:Tpl2/Cot activity was directly assayed using GST-MEK1 as a substrate. The phosphorylation on serine residues was detected by an ELISA. IC50 calculati...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2008
Entry Details Article
PubMed