BDBM21919 8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-({[6-(morpholin-4-yl)pyridin-2-yl]methyl}amino)quinoline-3-carbonitrile::Cyanoquinoline, 32

SMILES Fc1ccc(Nc2c(cnc3c(Cl)cc(NCc4cccc(n4)N4CCOCC4)cc23)C#N)cc1Cl

InChI Key InChIKey=VIIMQDOONHSFRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21919   

LigandPNGBDBM21919(8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-({[6...)
Affinity DataIC50: 350nMpH: 7.2 T: 2°CAssay Description:Tpl2/Cot activity was directly assayed using GST-MEK1 as a substrate. The phosphorylation on serine residues was detected by an ELISA. IC50 calculati...More data for this Ligand-Target Pair
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Date in BDB:
4/30/2008
Entry Details Article
PubMed