BDBM219264 US9303033, E34, Table 39A, Compound 1::US9303033, I17, Table 33A, Compound 80

SMILES Clc1cccc(Oc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1

InChI Key InChIKey=RPCMXNFXSNSLCR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 219264   

TargetCasein kinase II subunit alpha/beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM219264(US9303033, E34, Table 39A, Compound 1 | US9303033,...)
Affinity DataIC50: 10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
US Patent

TargetCasein kinase II subunit alpha/beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM219264(US9303033, E34, Table 39A, Compound 1 | US9303033,...)
Affinity DataIC50: 10nMpH: 7.2Assay Description:In a final reaction volume of 50 μl, CK2 ααββ (4 ng, 8.5 mU) was incubated with various concentrations of test compounds in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
US Patent

TargetCasein kinase II subunit beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM219264(US9303033, E34, Table 39A, Compound 1 | US9303033,...)
Affinity DataIC50: 1.19E+3nMpH: 7.0Assay Description:5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
US Patent

TargetCasein kinase II subunit beta(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM219264(US9303033, E34, Table 39A, Compound 1 | US9303033,...)
Affinity DataIC50: 2.50E+3nMpH: 7.0Assay Description:Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5× Reaction Buffer (40 mM MOPS pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2017
Entry Details
US Patent