BDBM21962 3-[(4S)-4-amino-5-[(2-aminoethyl)(hydroxy)amino]pentyl]-1-nitroguanidine::N omega-Nitro-L-Arginine-Containing Dipeptide, 3

SMILES NCCN(O)C[C@@H](N)CCCN=C(N)N[N+]([O-])=O

InChI Key InChIKey=HUOGRSGQHCPAGO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21962   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

LigandPNGBDBM21962(3-[(4S)-4-amino-5-[(2-aminoethyl)(hydroxy)amino]pe...)
Affinity DataKi:  120nM ΔG°:  -9.59kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM21962(3-[(4S)-4-amino-5-[(2-aminoethyl)(hydroxy)amino]pe...)
Affinity DataKi:  1.60E+4nM ΔG°:  -6.65kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

LigandPNGBDBM21962(3-[(4S)-4-amino-5-[(2-aminoethyl)(hydroxy)amino]pe...)
Affinity DataKi:  7.30E+4nM ΔG°:  -5.73kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed