BDBM21963 3-[(4S)-4-amino-5-[1-(2-aminoethyl)hydrazin-1-yl]pentyl]-1-nitroguanidine::N omega-Nitro-L-Arginine-Containing Dipeptide, 4

SMILES NCCN(N)C[C@@H](N)CCCN=C(N)N[N+]([O-])=O

InChI Key InChIKey=ODAAZRWLWWTAJR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21963   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

LigandPNGBDBM21963(3-[(4S)-4-amino-5-[1-(2-aminoethyl)hydrazin-1-yl]p...)
Affinity DataKi:  560nM ΔG°:  -8.67kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM21963(3-[(4S)-4-amino-5-[1-(2-aminoethyl)hydrazin-1-yl]p...)
Affinity DataKi:  3.70E+4nM ΔG°:  -6.14kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

LigandPNGBDBM21963(3-[(4S)-4-amino-5-[1-(2-aminoethyl)hydrazin-1-yl]p...)
Affinity DataKi:  1.03E+5nM ΔG°:  -5.53kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed