BDBM21991 5-{[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]carbonyl}-3-methyl-1-(2-methylpropyl)-6-(quinolin-4-ylmethyl)-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione::Thienopyrimidine-2,4-dione, 6

SMILES CC(C)Cn1c2sc(Cc3ccnc4ccccc34)c(C(=O)N3C[C@H](O)[C@H](O)C3)c2c(=O)n(C)c1=O

InChI Key InChIKey=QZXVZHLMQIJVHV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21991   

TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandPNGBDBM21991(5-{[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]carbonyl}...)
Affinity DataKi:  29nM ΔG°:  -10.2kcal/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed