BDBM21996 5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3-methyl-1-(2-methylpropyl)-6-{1H-pyrrolo[2,3-b]pyridin-3-ylmethyl}-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione::Thienopyrimidine-2,4-dione, 11

SMILES CC(C)Cn1c2sc(Cc3c[nH]c4ncccc34)c(C(=O)N3C[C@H](O)CO3)c2c(=O)n(C)c1=O

InChI Key InChIKey=HMICMRQBKBXVSC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 21996   

TargetMonocarboxylate transporter 1(Human)
Astrazeneca

LigandPNGBDBM21996(5-{[(4S)-4-hydroxy-1,2-oxazolidin-2-yl]carbonyl}-3...)
Affinity DataKi:  0.430nM ΔG°:  -12.6kcal/molepH: 7.8 T: 2°CAssay Description:Jurkat cell membranes were incubated with [3H]-labeled ligand in the absence or presence of increasing concentrations of test compound. The reagents ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2008
Entry Details Article
PubMed