BDBM220245 US9290476, 90A::US9290476, 90B::US9290476, 90C

SMILES CCc1nc2ccc(cc2c(Cl)c1Cc1ccc(cc1)C(F)(F)F)C(O)(C1CN(C1)C(C)=O)c1cnnn1C

InChI Key InChIKey=MYGPDLVYCIXIBI-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 220245   

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220245(US9290476, 90C | US9290476, 90B | US9290476, 90A)
Affinity DataKd:  0.320nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220245(US9290476, 90C | US9290476, 90B | US9290476, 90A)
Affinity DataKd:  0.440nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM220245(US9290476, 90C | US9290476, 90B | US9290476, 90A)
Affinity DataKd:  0.560nMpH: 7.0 T: 2°CAssay Description:Bar-coded assay plates are robotically loaded onto a thermostatically controlled PCR-type thermal block and then heated at a typical ramp-rate of 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent