BDBM221043 US9284322, Table 6, Compound 9
SMILES Nc1cc(ccn1)-c1cc(cnc1F)C1CC2CCC1N2
InChI Key InChIKey=ZALPTLPCTBOPDH-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 221043
TargetIsoform Alpha-4-2 of Neuronal acetylcholine receptor subunit alpha-4 (Alpha-4-2)/Neuronal acetylcholine receptor subunit beta-2(Rat)
Research Triangle Institute
US Patent
Research Triangle Institute
US Patent
Affinity DataKi: 0.130nM ΔG°: -13.5kcal/molepH: 7.4 T: 25°CAssay Description:Adult male rat cerebral cortices (Pelfreeze Biological, Rogers, Ark.) were homogenized in 39 volumes of ice-cold 50 mM Tris buffer (pH 7.4 at 4° C.) ...More data for this Ligand-Target Pair
Affinity DataKi: 719nMpH: 7.4Assay Description:Adult male rat cerebral cortices (Pel-Freez Biologicals, Rogers, Ark.) were homogenized (polytron) in 39 volumes of ice-cold 50 mM Tris buffer (assay...More data for this Ligand-Target Pair