BDBM22147 (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(1,2-oxazol-3-ylamino)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(isoxazol-3-ylamino)-6-(1-methylethyl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::isoxazole compound, 9a
SMILES CC(C)c1nc(Nc2ccon2)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O
InChI Key InChIKey=KTZCMSGWDSHEMY-NXVGNOFTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 22147
Affinity DataIC50: 2.30nM EC50: 1.40nMpH: 7.0 T: 37°CAssay Description:Enzyme Assay for HMG-CoA reductase was based on the conversion of isotopically labeled HMG-CoA to mevalonic acid using rat liver microsomes as enzyme...More data for this Ligand-Target Pair