BDBM22168 (1S)-3-(4-{2-[bis(4-fluorophenyl)methoxy]ethyl}piperazin-1-yl)-1-phenylpropan-1-ol::CHEMBL26478::GBR 12935 Analogue, (S)-3
SMILES O[C@@H](CCN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccccc1
InChI Key InChIKey=FRNMVZXBCHKPGE-MHZLTWQESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 22168
Affinity DataKi: 4.40nM ΔG°: -10.6kcal/molepH: 7.4 T: 2°CAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Binding affinity against dopamine transporter labelled with [125I]- RTI-55 in rat.More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Binding affinity for dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 135nMAssay Description:Binding affinity for serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 135nMAssay Description:Binding affinity against Serotonin transporter (SERT) labelled with [125I]-RTI-55 in rat.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 135nM ΔG°: -8.71kcal/molepH: 7.4 T: 2°CAssay Description:The assay was initiated by the addition of membranes to binding buffer containing test compound, blocker, and radioligand. The samples were incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Reuptake inhibition of [3H]-labeled dopamine (DA) in rat.More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataIC50: 178nMAssay Description:Reuptake inhibition of [3H]-5-HT (5-HT) in rat.More data for this Ligand-Target Pair