BDBM221761 US9314468, Table 7, Compound 48::US9314468, Table 9, Compound 1

SMILES NCCCCN(Cc1nccc2c3ccccc3n(CC(=O)N3CCOCC3)c12)[C@H]1CCCc2cccnc12

InChI Key InChIKey=PBOCFANSMNVTHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 221761   

TargetC-X-C chemokine receptor type 4(Human)
Altiris Therapeutics

US Patent
LigandPNGBDBM221761(US9314468, Table 9, Compound 1 | US9314468, Table ...)
Affinity DataIC50: 12nMT: 2°CAssay Description:Functional modulation of CXCR4 was determined by calcium mobilization assay using leukemic lymphoid CEM cells, which naturally express high levels of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetC-X-C chemokine receptor type 4(Human)
Altiris Therapeutics

US Patent
LigandPNGBDBM221761(US9314468, Table 9, Compound 1 | US9314468, Table ...)
Affinity DataIC50: 79nMT: 2°CAssay Description:Functional modulation of CXCR4 was determined by calcium mobilization assay using leukemic lymphoid CEM cells, which naturally express high levels of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent