BDBM221825 US9314468, Table 7, Compound 112::US9314468, Table 9, Compound 14

SMILES NCCCCN(Cc1nccc2c3ccccc3n(CC(N)=O)c12)[C@H]1CCCc2cccnc12

InChI Key InChIKey=ABDLOXDCMBBRCJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 221825   

TargetC-X-C chemokine receptor type 4(Human)
Altiris Therapeutics

US Patent
LigandPNGBDBM221825(US9314468, Table 9, Compound 14 | US9314468, Table...)
Affinity DataIC50: 17nMT: 2°CAssay Description:Functional modulation of CXCR4 was determined by calcium mobilization assay using leukemic lymphoid CEM cells, which naturally express high levels of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetC-X-C chemokine receptor type 4(Human)
Altiris Therapeutics

US Patent
LigandPNGBDBM221825(US9314468, Table 9, Compound 14 | US9314468, Table...)
Affinity DataIC50: 18nMT: 2°CAssay Description:Functional modulation of CXCR4 was determined by calcium mobilization assay using leukemic lymphoid CEM cells, which naturally express high levels of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Altiris Therapeutics

US Patent
LigandPNGBDBM221825(US9314468, Table 9, Compound 14 | US9314468, Table...)
Affinity DataIC50: 1.80E+3nMT: 2°CAssay Description:The in vitro effects of the selected compounds on the hERG (human ether- -go-go-related gene) potassium channel current (a surrogate for IKr, the rap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
US Patent