BDBM222119 2-(4-Methylphenyl)-4H-3,1-benzoxazin-4-one (7)

SMILES Cc1ccc(cc1)-c1nc2ccccc2c(=O)o1

InChI Key InChIKey=AUPLZGYHNMXILO-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 222119   

TargetChymotrypsinogen A(Bovine)
University of Karachi

LigandPNGBDBM222119(2-(4-Methylphenyl)-4H-3,1-benzoxazin-4-one (7))
Affinity DataKi:  1.64E+4nMAssay Description:The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2017
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
University of Karachi

LigandPNGBDBM222119(2-(4-Methylphenyl)-4H-3,1-benzoxazin-4-one (7))
Affinity DataIC50: 2.01E+4nMpH: 7.6Assay Description:The α-chymotrypsin inhibition activity was evaluated in 50 mM Tris-HCl buffer pH 7.6 with 10 mM CaCl2. α-Chymotrypsin (bovine pancreas) at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM222119(2-(4-Methylphenyl)-4H-3,1-benzoxazin-4-one (7))
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]NECA from Sprague-Dawley rat striatal membrane A2A adenosine receptor by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM222119(2-(4-Methylphenyl)-4H-3,1-benzoxazin-4-one (7))
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]DPCPX from Sprague-Dawley rat whole brain membrane A1AR by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed