BDBM22218 1,2,4-oxadiazole based compound, 35::1-[(4-{5-[4-(3,3,3-trifluoropropyl)phenyl]-1,2,4-oxadiazol-3-yl}phenyl)methyl]azetidine-3-carboxylic acid

SMILES OC(=O)C1CN(Cc2ccc(cc2)-c2noc(n2)-c2ccc(CCC(F)(F)F)cc2)C1

InChI Key InChIKey=XYFAADCQOGUWOC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22218   

TargetSphingosine 1-phosphate receptor 5(Human)
Merck Research Laboratories

LigandPNGBDBM22218(1-[(4-{5-[4-(3,3,3-trifluoropropyl)phenyl]-1,2,4-o...)
Affinity DataIC50: 0.300nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

LigandPNGBDBM22218(1-[(4-{5-[4-(3,3,3-trifluoropropyl)phenyl]-1,2,4-o...)
Affinity DataIC50: 0.400nMpH: 7.5 T: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Merck Research Laboratories

LigandPNGBDBM22218(1-[(4-{5-[4-(3,3,3-trifluoropropyl)phenyl]-1,2,4-o...)
Affinity DataIC50: 430nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

LigandPNGBDBM22218(1-[(4-{5-[4-(3,3,3-trifluoropropyl)phenyl]-1,2,4-o...)
Affinity DataIC50: 1.30E+4nMT: 2°CAssay Description:The assay measures the displacement of [33P]-labeled sphingosine-1-phosphate (S1P) by test compounds from human S1P receptors expressed on CHO cell m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2008
Entry Details Article
PubMed