BDBM222667 US9315491, MTR-0477::US9801888, Compound MTR-0477

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c(SC)c(n1)-c1ccncc1

InChI Key InChIKey=FHGYEYAVCXNZFJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222667   

TargetSerine/threonine-protein kinase mTOR(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM222667(US9315491, MTR-0477 | US9801888, Compound MTR-0477)
Affinity DataIC50: 23.7nMpH: 7.5Assay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Development Center For Biotechnology

US Patent
LigandPNGBDBM222667(US9315491, MTR-0477 | US9801888, Compound MTR-0477)
Affinity DataIC50: 23.7nMAssay Description:The activity of the compound against mTOR was examined by measuring the incorporation of 33P from [γ-33P]-ATP into 4EBP1. His-tagged, recombinan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2019
Entry Details
US Patent