BDBM222749 US9315498, 37

SMILES CC1(C)CN(C(=O)C1)c1ccc(cn1)C#Cc1cncc(F)c1

InChI Key InChIKey=WCSCMCRCRMPYSU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222749   

TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM222749(US9315498, 37)
Affinity DataEC50:  22nMT: 2°CAssay Description:A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2017
Entry Details
US Patent