BDBM223541 US9321748, 1

SMILES CC(C)c1nnc(o1)-c1cc(cnc1N)-c1ccc2[nH]ccc2c1

InChI Key InChIKey=YNLOBEMSGACSSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223541   

LigandPNGBDBM223541(US9321748, 1)
Affinity DataIC50: 910nMpH: 8.5 T: 2°CAssay Description:The kinase reaction buffer consists of 50 mM Tris pH 8.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, and 2 mM DTT. In the assay, 1 nM LRRK2 WT or 250 pM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

LigandPNGBDBM223541(US9321748, 1)
Affinity DataIC50: 910nMAssay Description:Inhibition of recombinant human LRRK2 (970 to 2527 residues) G2019S mutant expressed in baculovirus preincubated for 30 mins followed by fluorescein-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2020
Entry Details Article
PubMed