BDBM223557 US9321748, 17

SMILES COc1cc(ccc1C(=O)N1CCOCC1)-c1cnc(N)c(c1)-c1cn(nn1)C(C)C

InChI Key InChIKey=WTMSPLKBPPJPHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 223557   

LigandPNGBDBM223557(US9321748, 17)
Affinity DataIC50: 91nMpH: 8.5 T: 2°CAssay Description:The kinase reaction buffer consists of 50 mM Tris pH 8.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, and 2 mM DTT. In the assay, 1 nM LRRK2 WT or 250 pM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent

LigandPNGBDBM223557(US9321748, 17)
Affinity DataIC50: 95nMpH: 8.5 T: 2°CAssay Description:The kinase reaction buffer consists of 50 mM Tris pH 8.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, and 2 mM DTT. In the assay, 1 nM LRRK2 WT or 250 pM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
US Patent