BDBM223989 A-395N (6)
SMILES CN(C)[C@@H]1CN(Cc2ccccc2)C[C@H]1c1ccc(cc1)N1CCN(CC1)S(C)(=O)=O
InChI Key InChIKey=VEABDKBNQNHHCB-BJKOFHAPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 223989
Affinity DataKi: 1.83E+3nM ΔG°: -7.82kcal/molepH: 7.5 T: 2°CAssay Description:For the assay, compounds were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM to ~850 pM using an Echo 550 Acousti...More data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMpH: 7.5 T: 2°CAssay Description:For the assay, compounds or nonbiotinylated H3(23-34) peptide were dispensed in assay-ready plates using a three-fold serial dilution from 50 μM...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMT: 2°CAssay Description:IC50 values were determined for compounds A-395 and A-395N at 75 nM of EZH2 trimeric complex (EZH2-EED-SUZ12), 3 μM of human nucleosome and 1 ...More data for this Ligand-Target Pair