BDBM224589 US10202383, Example 2(96)::US9321791, 2(96)::US9556175, 2(96)

SMILES C\C=C\Cn1c(nc2n(C)c(=O)n(CC(=O)c3ccccc3NC(C)=O)c(=O)c12)N1CCCC(N)C1

InChI Key InChIKey=JURAVIOFGULDFB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224589   

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224589(US9556175, 2(96) | US9321791, 2(96) | US10202383, ...)
Affinity DataIC50: 2nMpH: 7.8Assay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224589(US9556175, 2(96) | US9321791, 2(96) | US10202383, ...)
Affinity DataIC50: 2nMAssay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224589(US9556175, 2(96) | US9321791, 2(96) | US10202383, ...)
Affinity DataIC50: 2nMpH: 7.8Assay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
US Patent