BDBM224607 US10202383, Example 2(251)::US9321791, 2(251)::US9556175, 2(251)

SMILES CC#CCn1c(nc2n(C)c(=O)n(Cc3ccc(F)c4ccccc34)c(=O)c12)N1CCC[C@@H](N)C1

InChI Key InChIKey=IPXGVJNUIXIPRI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224607   

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224607(US9556175, 2(251) | US9321791, 2(251) | US10202383...)
Affinity DataIC50: 12nMAssay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224607(US9556175, 2(251) | US9321791, 2(251) | US10202383...)
Affinity DataIC50: 12nMpH: 7.8Assay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
US Patent

TargetDipeptidyl peptidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM224607(US9556175, 2(251) | US9321791, 2(251) | US10202383...)
Affinity DataIC50: 12nMpH: 7.8Assay Description:50 μl substrate solution (AFC; AFC is amido-4-trifluoromethylcoumarin), final concentration 100 μM, were placed in black microtitre plates. 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
US Patent