BDBM225084 US9321756, 53

SMILES FC(F)(F)CNc1nnc(o1)-c1ccc2[nH]cc(-c3nccc(n3)C3CC3)c2c1

InChI Key InChIKey=YVAQXIXCFJWYDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225084   

TargetSerine/threonine-protein kinase pim-1(Human)
Amgen

US Patent
LigandPNGBDBM225084(US9321756, 53)
Affinity DataIC50: 0.407nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Amgen

US Patent
LigandPNGBDBM225084(US9321756, 53)
Affinity DataIC50: 0.638nMAssay Description:The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2017
Entry Details
US Patent