BDBM225125 US9328118, 26
SMILES CCN1CCC(CCOc2ccc(cc2C(F)(F)F)-c2nc(nc3n(C)cnc23)C#N)CC1
InChI Key InChIKey=PJAXLEWBMOURNH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 225125
Affinity DataIC50: 0.610nMAssay Description:First, spleen cells collected from C57BL/6 mice were seeded in a 96-well plate so as to be a 1× 105 cells/well, then, 5-fold dilution of 10 mM DMSO s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:5 μL of a human cathepsin S enzyme (R&D1183-CY-010) was added to a 96-well plate so as to be 20 ng/well. Next, 10-fold dilution of the test comp...More data for this Ligand-Target Pair