BDBM2253 2-Pyridinone derivative 33::3-[2-(7-Chlorobenzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridine-2(1H)-thione::3-[2-(7-chloro-1,3-benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-1,2-dihydropyridine-2-thione::CHEMBL174130
SMILES CCc1cc(CCc2nc3cccc(Cl)c3o2)c(=S)[nH]c1C
InChI Key InChIKey=IVRVASYPWHAIIN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 2253
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Merck Reserch Laboratories
Curated by ChEMBL
Merck Reserch Laboratories
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Reserch Laboratories
Curated by ChEMBL
Merck Reserch Laboratories
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair