BDBM226314 US9328096, 7

SMILES C[C@H]%11Cc1c([nH]c2ccccc12)[C@H](c%10cnc(N3CCC9(CC3)C[C@H](CN8CCN7c6cc5CN([C@@H]4CCC(=O)NC4=O)C(=O)c5cc6OC[C@@H]7C8)CO9)nc%10)N%11CC(F)F

InChI Key InChIKey=ROLXITLMLYYQAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 226314   

TargetEstrogen receptor [282-595](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 226314BDBM226314((R)-3-((S)-3-(((R)-8-(5-((1S,3S)-2-(2,2- difluoroe...)
Affinity DataIC50: 10nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 226314BDBM226314((R)-3-((S)-3-(((R)-8-(5-((1S,3S)-2-(2,2- difluoroe...)
Affinity DataIC50: 275nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2026
Entry Details
US Patent