BDBM2268 2-Pyridinone derivative 48::3-[2-(1,3-benzoxazol-2-yl)ethyl]-6-methyl-5-(propan-2-yl)-1,2-dihydropyridin-2-one::3-[2-(Benzoxazol-2-yl)ethyl]-5-isopropyl-6-methylpyridin-2(1H)-one::CHEMBL176594

SMILES CC(C)c1cc(CCc2nc3ccccc3o2)c(=O)[nH]c1C

InChI Key InChIKey=FOHQBRBSZDTCTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2268   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Merck Reserch Laboratories

Curated by ChEMBL
LigandPNGBDBM2268(2-Pyridinone derivative 48 | 3-[2-(1,3-benzoxazol-...)
Affinity DataIC50:  48nMAssay Description:Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Reserch Laboratories

Curated by ChEMBL
LigandPNGBDBM2268(2-Pyridinone derivative 48 | 3-[2-(1,3-benzoxazol-...)
Affinity DataIC50:  48nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed