BDBM227026 US9328096, 714

SMILES C=Cc1cc(C2(c3nncn3C)CC(C)C2)cc(-n2cnc3c(C(F)(F)F)cc(CN4CCC[C@H](C)C4)cc3c2=O)n1

InChI Key InChIKey=FYAABJULMNOBPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227026   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 227026BDBM227026(US20260008770, Example 49)
Affinity DataIC50: 20nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent