BDBM227028 US20260008770, Example 51

SMILES C#Cc1cc(-n2cc3c(C(F)(F)F)cc(CN4CCC[C@H](C)C4)cc3n2)cc(C2(c3nncn3C)CC(C)C2)c1

InChI Key InChIKey=GWVKCMQHMMFGAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227028   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Insilico Medicine IP

US Patent
LigandChemical structure of BindingDB Monomer ID 227028BDBM227028(US20260008770, Example 51)
Affinity DataIC50: 275nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent