BDBM227055 US9328096, 743

SMILES C[C@H]1CCCN(Cc2cc(C(F)(F)F)c3ncn(-c4cc([C@]5(c6nncn6C)C[C@@H](C)C5)ccn4)c(=O)c3c2)C1

InChI Key InChIKey=BFQZROJGZSFWMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227055   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 227055BDBM227055(US20260008770, Example 78)
Affinity DataIC50: 20nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent