BDBM227090 US9328096, 778

SMILES [2H]c1nnc(C2(c3ccnc(-n4cnc5c(C(F)(F)F)cc(CN6CCC[C@H](C)C6)cc5c4=O)c3)CC(C)C2)n1C(F)F

InChI Key InChIKey=RBCLJCPGOKDZEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227090   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 227090BDBM227090(US20260008770, Example 113)
Affinity DataIC50: 20nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2026
Entry Details
US Patent