BDBM22712 Bicyclic pyrimidinone, (S)-28c::N-[(10S)-2-{[(4-fluorophenyl)methyl]carbamoyl}-3-hydroxy-4-oxo-4H,6H,7H,8H,9H,10H-pyrimido[1,2-a]azepin-10-yl]-N',N',N''-trimethylethanediamide

SMILES CN(C)C(=O)C(=O)N(C)[C@H]1CCCCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O

InChI Key InChIKey=WBQCKUNNRLRPOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22712   

TargetGag-Pol polyprotein(HIV-1)
Irbm-Mrl

LigandPNGBDBM22712(N-[(10S)-2-{[(4-fluorophenyl)methyl]carbamoyl}-3-h...)
Affinity DataIC50: 12nMAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2008
Entry Details Article
PubMed