BDBM227447 US9328106, 400

SMILES Cn1ncc(NC(=O)c2csc(n2)-c2c(F)ccc3[nH]ccc23)c1[C@@H]1CC[C@@H](N)[C@H](F)CO1

InChI Key InChIKey=UFWYZTSTUAFGDC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227447   

TargetSerine/threonine-protein kinase pim-1(Human)
Genentech

US Patent
LigandPNGBDBM227447(US9328106, 400)
Affinity DataKi:  0.0110nM ΔG°:  -14.9kcal/molepH: 7.2 T: 2°CAssay Description:LC3K assay: PIM-1, -2, and -3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
US Patent