BDBM227456 US9333205, 55

SMILES COc1cc(ccc1Nc1ncc2c(n1)-c1onc(C(N)=O)c1CC2(C)C)C(=O)NC1CCN(C)CC1

InChI Key InChIKey=FHHZNSDJYAYZQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 227456   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM227456(US9333205, 55)
Affinity DataIC50: 510nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
US Patent

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM227456(US9333205, 55)
Affinity DataIC50: 3.44E+3nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
US Patent