BDBM227739 BDBM228957::US9328099, 47-4::US9540377, 6.85
SMILES CC(C)C1CCCN1c1nc(nc2nc(-c3cccc(C)c3)n(Cc3ccc(cc3)C(F)(F)F)c12)C(O)=O
InChI Key InChIKey=FVZMIQVDOOOLTF-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 227739
Affinity DataIC50: 1nMT: 2°CAssay Description:The reactions employed a common peptide substrate, LCB-EQEDEPEGDYFEWLW-NH2 (in-house). The basic assay protocol is as follows: First, 250 nL of dilut...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMT: 2°CAssay Description:The reactions employed a common peptide substrate, LCB-EQEDEPEGDYFEWLW-NH2 (in-house). The basic assay protocol is as follows: First, 250 nL of dilut...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMT: 2°CAssay Description:The reactions employed a common peptide substrate, LCB-EQEDEPEGDYFEWLW-NH2 (in-house). The basic assay protocol is as follows: First, 250 nL of dilut...More data for this Ligand-Target Pair
Affinity DataIC50: 83nMT: 2°CAssay Description:The reactions employed a common peptide substrate, LCB-EQEDEPEGDYFEWLW-NH2 (in-house). The basic assay protocol is as follows: First, 250 nL of dilut...More data for this Ligand-Target Pair
Affinity DataIC50: 723nMT: 2°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair