BDBM227745 isoindolinone analog 2

SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)N1C3C=CC=CC3C3=C1C1=C(C4C=CC=CC4N21)C1C3CNC1=O

InChI Key InChIKey=QKEWRTCTQHZYJK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227745   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM227745(isoindolinone analog 2)
Affinity DataIC50: 115nMpH: 7.4 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2005
Entry Details Article
PubMed