BDBM227909 US10047096, 170::US10047096, 171::US10047096, 213::US10047096, 214::rac-8-[(3,4-cis-Dihydroxypiperidin-1-yl)methyl]-4-[(2-fluoro-5-hydroxy-4-methylphenyl)amino]-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-one
SMILES Cc1cc(F)c(Nc2ccnc3Nc4ccc(CN5CCC(O)C(O)C5)cc4NC(=O)c23)cc1O
InChI Key InChIKey=UMFBYZXXIZIFTP-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 227909
Affinity DataIC50: 0.618nMpH: 7.0Assay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human KDR (amino acids D807-V1356), expresse...More data for this Ligand-Target Pair
Affinity DataIC50: 0.806nMpH: 7.0Assay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human KDR (amino acids D807-V1356), expresse...More data for this Ligand-Target Pair
Affinity DataIC50: 0.929nMpH: 7.0Assay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human KDR (amino acids D807-V1356), expresse...More data for this Ligand-Target Pair
Affinity DataIC50: 1.05nMpH: 7.5 T: 2°CAssay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human PDGFR (amino acids R561-L1106), expres...More data for this Ligand-Target Pair
Affinity DataIC50: 1.37nMpH: 7.5 T: 2°CAssay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human PDGFR (amino acids R561-L1106), expres...More data for this Ligand-Target Pair
Affinity DataIC50: 1.39nMpH: 7.0Assay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human KDR (amino acids D807-V1356), expresse...More data for this Ligand-Target Pair
Affinity DataIC50: 1.58nMpH: 7.5 T: 2°CAssay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human PDGFR (amino acids R561-L1106), expres...More data for this Ligand-Target Pair
Affinity DataIC50: 2.56nMpH: 7.5 T: 2°CAssay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human PDGFR (amino acids R561-L1106), expres...More data for this Ligand-Target Pair