BDBM228155 (R)-5-(2-morpholino-5a,6,8,9-tetrahydro-5H- pyrimido[5',4':4,5]pyrrolo[2,1-c][1,4]oxazin-4- yl)-4-(trifluoromethyl)pyridin-2-amine::US9556203, 38

SMILES Nc5cc(C(F)(F)F)c(c2nc(N1CCOCC1)nc3c2C[C@@H]4COCCN34)cn5

InChI Key InChIKey=GLPWETMUURNSHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228155   

LigandChemical structure of BindingDB Monomer ID 228155BDBM228155((R)-5-(2-morpholino-5a,6,8,9-tetrahydro-5H- pyrimi...)
Affinity DataIC50: 2.62E+3nMAssay Description:N-terminally His-tagged PI3K alpha (Cat. No. PV4789; 0.49 mg/ml), Alexa Fluor 647 labeled kinase Tracer 314 (Cat. No. PV6087), Biotin anti-His Tag an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2018
Entry Details
US Patent